全文获取类型
收费全文 | 130727篇 |
免费 | 23293篇 |
国内免费 | 9205篇 |
出版年
2023年 | 1276篇 |
2022年 | 1773篇 |
2021年 | 5366篇 |
2020年 | 5450篇 |
2019年 | 7795篇 |
2018年 | 7769篇 |
2017年 | 7266篇 |
2016年 | 8553篇 |
2015年 | 9923篇 |
2014年 | 11193篇 |
2013年 | 11958篇 |
2012年 | 11415篇 |
2011年 | 10261篇 |
2010年 | 8611篇 |
2009年 | 6832篇 |
2008年 | 6651篇 |
2007年 | 5667篇 |
2006年 | 4964篇 |
2005年 | 4216篇 |
2004年 | 3662篇 |
2003年 | 3423篇 |
2002年 | 2802篇 |
2001年 | 2342篇 |
2000年 | 2001篇 |
1999年 | 1551篇 |
1998年 | 951篇 |
1997年 | 829篇 |
1996年 | 811篇 |
1995年 | 768篇 |
1994年 | 732篇 |
1993年 | 569篇 |
1992年 | 774篇 |
1991年 | 620篇 |
1990年 | 535篇 |
1989年 | 478篇 |
1988年 | 352篇 |
1987年 | 377篇 |
1986年 | 345篇 |
1985年 | 294篇 |
1984年 | 230篇 |
1983年 | 231篇 |
1982年 | 172篇 |
1981年 | 134篇 |
1980年 | 110篇 |
1979年 | 139篇 |
1978年 | 106篇 |
1976年 | 105篇 |
1974年 | 101篇 |
1973年 | 113篇 |
1972年 | 106篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
51.
Nutrients are assimilated efficiently by Lymantria dispar caterpillars from the mature leaves of trees in the Salicaceae 下载免费PDF全文
Raymond V. Barbehenn Jennifer Knister Frank Marsik Chelsea Jahant‐Miller William Nham 《Physiological Entomology》2015,40(1):72-81
The efficient aquisition of nutrients from leaves by insect herbivores increases their nutrient assimilation rates and overall fitness. Caterpillars of the gypsy moth (Lymantria dispar L.) have high protein assimilation efficiencies (PAE) from the immature leaves of trees such as red oak (Quercus rubra) and sugar maple (Acer saccharum) (71–81%) but significantly lower PAE from their mature leaves (45–52%). By contrast to this pattern, both PAE and carbohydrate assimilation efficiencies (CAE) remain high for L. dispar larvae on the mature leaves of poplar (Populus alba × Populus tremula) grown in greenhouse conditions. The present study tests two alternative hypotheses: (i) outdoor environmental stresses cause decreased nutrient assimilation efficiencies from mature poplar leaves and (ii) nutrients in the mature leaves of trees in the poplar family (Salicaceae) remain readily available for L. dispar larvae. When poplar trees are grown in ambient outdoor conditions, PAE and CAE remain high (approximately 75% and 78%, respectively) in L. dispar larvae, in contrast to the first hypothesis. When larvae feed on the mature leaves of species in the Salicaceae [aspen (Populus tremuloides), cottonwood (Populus deltoides), willow (Salix nigra) and poplar], PAE and CAE also remain high (68–76% and 72–92%, respectively), consistent with the second hypothesis. Larval growth rates are strongly associated with protein assimilation rates, and more strongly associated with protein assimilation rates than with carbohydrate assimilation rates. It is concluded that tree species in the Salicaceae are relatively high‐quality host plants for L. dispar larvae, in part, because nutrients in their mature leaves remain readily available. 相似文献
52.
53.
54.
55.
56.
Hypertension is an independent risk factor for the progression of chronic renal failure, and oxidative stress plays a critical role in hypertensive renal damage. Forkbox O1(FoxO1) signaling protects cells against oxidative stress and may be a useful target for treating oxidative stress-induced hypertension. Tongxinluo is a traditional Chinese medicine with cardioprotective and renoprotective functions. Therefore, this study aimed to determine the effects of Tongxinluo in hypertensive renal damage in spontaneously hypertensive rats(SHRs)and elucidate the possible involvement of oxidative stress and FoxO1 signaling in its molecular mechanisms. SHRs treated with Tongxinluo for 12 weeks showed a reduction in systolic blood pressure. In addition to increasing creatinine clearance, Tongxinluo decreased urinary albumin excretion, oxidative stress injury markers including malondialdehyde and protein carbonyls, and expression of nicotinamide adenine dinucleotide phosphate oxidase subunits and its activity in SHR kidneys. While decreasing phosphorylation of FoxO1, Tongxinluo also inhibited the phosphorylation of extracellular signal-regulated kinase1/2 and p38 and enhanced manganese superoxide dismutase and catalase activities in SHR kidneys. Furthermore, histology revealed attenuation of glomerulosclerosis and renal podocyte injury, while Tongxinluo decreased the expression of α-smooth muscle actin, extracellular matrixprotein, transforming growth factor β1 and small mothers against decapentaplegic homolog 3,and improved tubulointerstitial fibrosis in SHR kidneys. Finally, Tongxinluo inhibited inflammatory cell infiltration as well as expression of tumor necrosis factor-α and interleukin-6. In conclusion, Tongxinluo protected SHRs against hypertension-induced renal injury by exerting antioxidant, antifibrotic, and anti-inflammatory activities. Moreover, the underlying mechanisms of these effects may involve inhibition of oxidative stress and functional activation of FoxO1 signaling. 相似文献
57.
58.
59.
60.
Seismic and auditory tuning curves from bullfrog saccular and amphibian papular axons 总被引:1,自引:0,他引:1
Xiaolong Yu Edwin R. Lewis David Feld 《Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology》1991,169(2):241-248
We present seismic and auditory frequency tuning curves of individual bullfrog, Rana catesbeiana, saccular and amphibian papilla axons that responded to both seismic and auditory stimuli. In this study we found: 1) most saccular axons respond well to auditory stimuli with moderate signal strength (50-70 dB SPL) as well as to seismic stimuli; 2) most amphibian papilla axons respond well to seismic stimuli as well as to auditory stimuli, and their seismic sensitivities are comparable to those of saccular axons (responding to sinusoidal stimuli with peak accelerations in the range 0.001 to 0.1 cm/S2); 3) the responses to both seismic and auditory stimuli from both saccule and amphibian papilla are tuned, i.e. the strength of the response varies with the frequency of the stimulus; and this tuning is clearly not the result of second order resonance; 4) in individual axons the tuning properties for seismic stimuli often are not the same as those for auditory stimuli, a fact that may provide clues about how the stimulus signal energy is transferred to the hair cells in each case. 相似文献